Daily Skin Care Regimen
DERMAHEAL TOTAL CARE SKIN SOLUTION 275g
Provides anti-aging, anti-pigmentation and anti-oxidation effects. Removes dirt, oil and provides the skin with a fresh and clean feeling by moisturizing effect. Keeps pH balance and makes skin ready to absorb the active ingredients fully
DIRECTION FOR USE
Apply the skin solution over your face and neck after cleansing. Tap until it is absorbed. Use every morning and night.
ACTIVE INGREDIENTS
PT Oligopeptide-34(CG-TGP2), Oligopeptide-24(CG- EDP3), Tripeptide-6(CG-CTP), Copper Tripeptide-1,Adenosine, Retinyl Palmitate, Tocopheryl Acetate, Arbutin, Camellia Sinensis Leaf Extract, Scutellaria Baicalensis Root Extract, Vitis Vinifera (Grape) Seed Extract, Centella Asiatica Extract, Sodium Hyaluronate
DERMAHEAL HYDRO BALANCE FLUID 50g
Find skin glow with a fresh, flawless radiance. Now you can remove first signs of aging- uneven skin tone, dullness and fine dry lines. Comforts and cushions dry skin with soothing emollients and luscious texture. Guarantees genuine skin glow with a beautiful and healthy vitality.
DIRECTION FOR USE
Apply a small amount of the fluid over the face and neck. Massage with fingers over your skin. Let it penetrate and proceed with the Anti-Wrinkle Cream or Skin Delight Cream. Use every morning and night.
ACTIVE INGREDIENTS
PT Acetyl Decapeptide-3 (Rejuline), Oligopeptide-20 (CG-IDP5), Oligopeptide-24 (CG-EDP3), Palmitoyl Pentapeptide-3, Acetyl Hexapeptide-8, Copper Tripeptide-1, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Betaine, Panthenol
DERMAHEAL WRINKLE SKINCEUTICAL SERUM 20ml
Contains various growth factors and peptides, which improve the appearance of wrinkles by increasing the level of collagen, elastin and other ECMs (Extra Cellular Matrix).
DIRECTION FOR USE
Apply a small amount of the serum after pH balancing with skin solution. Massage from inside towards outside according to the skin texture. Use every morning and night.
ACTIVE INGREDIENTS
GF sh-Oligopeptide-1 (CG-EGF), sh-Oligopeptide-2 (CG-IGF1), sh-Polypeptide-1 (CG-bFGF), sh- Polypeptide-2 (CG-TRX), sh-Polypeptide-11(CG-aFGF), Acetyl Decapeptide-3 (Rejuline), Decapeptide-4 (CG-IDP2), Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-3, Copper Tripeptide-1, Sodium Hyaluronate, Ginkgo Biloba Leaf Extract, Epigallocatechin Gallate, Arbutin, Adenosine
Anti-Aging Care with Growth Factors and Peptides
Anti-aging product line contains high concentration of growth factors to prevent skin aging.
GROWTH FACTORS STIMULATE FIBROBLAST PROLIFERATION
CLINICAL STUDY FOR GROWTH FACTOR ANTI-AGING CREAM
GROWTH FACTORS INCREASE ECMS (EXTRA CELLULAR MATRIX)
Anti-Aging Care with Growth Factors and Peptides
Dermaheal Cosmeceutical Anti-wrinkle Serum 40ml
Maintains optimum moisture balance and keeps your skin radiant with supplying nourishment. Reduces and prevents wrinkles by generating new skin cells.
DIRECTION FOR USE
Apply a small amount of the serum on your face. Massage over face and neck with light circular motion until it is absorbed. Follow with Dermaheal Cosmeceutical Anti-wrinkle Cream. Use every morning and night.
ACTIVE INGREDIENTS
GF sh-Oligopeptide-1 (CG-EGF), sh-Oligopeptide-2 (CG-IGF1), sh-Polypeptide-1 (CG-bFGF), sh-Polypeptide-2 (CG-TRX), sh- Polypeptide-11(CG-aFGF), Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-3, Copper Tripeptide-1, Adenosine
PT Oligopeptide-24 (CG-EDP3), Decapeptide-4 (CG-IDP2), Acetyl Decapeptide-3 (Rejuline),Tripeptide-6 (CG-CTP), Oligopeptide-20 (CG-IDP5), Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-3, Arginin
Dermaheal Cosmeceutical Eye Cream 15ml
Slows down visible aging signs such as wrinkles and crow’s feet around eyes. Improves skin elasticity and gives you healthier and younger
DIRECTION FOR USE
Apply a small amount around eye area and pat until it is absorbed. Use every morning and night.
ACTIVE INGREDIENTS
GF sh-Oligopeptide-1 (CG-EGF), sh-Oligopeptide-2(CG-IGF1), sh-Polypeptide-1 (CG-bFGF), sh-Polypeptide-11 (CG-aFGF), sh-Polypeptide-2 (CG-TRX), Acetyl Hexapeptide-8, Copper Tripeptide-1, Butyrospermum Parkii (Shea) Butter,Betaine, Ginkgo Biloba Leaf Extract, Portulaca Oleracea Extract, Chlorella Vulgaris Extract, Tocopheryl Acetate, Adenosine, Sodium Hyaluronate
PT Oligopeptide-24 (CG-EDP3), Acetyl Decapeptide-3 (Rejuline), Oligopeptide-20 (CG-IDP5), Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Pentapeptide-3, Chlorella Vulgaris Extract, Ginkgo Biloba Leaf Extract, Portulaca Oleracea Extract, Butyrospermum Parkii (Shea) Butter, Adenosine
Dermaheal Cosmeceutical Anti-wrinkle Cream 40g
Visibly revives and re-energizes your skin. Reduces and prevents wrinkles by generating new skin cells and increasing skin elasticity from upregulation of collagen, elastin, fibro-nectin and hyaluronic acid.
DIRECTION FOR USE
Apply a small amount on your face and neck. Gently massage with light circular motion from inside towards outside. Use every morning and night.
ACTIVE INGREDIENTS
GF Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-3, sh-Oligopeptide-1 (CG-EGF), sh-Oligopeptide-2 (CG-IGF1), sh-Polypeptide-1(CG-bFGF), sh-Polypeptide-2 (CG-TRX), sh- Polypeptide-11 (CG-aFGF), Adenosine
PT Copper Tripeptide-1, Acetyl Hexapeptide-8, Decapeptide-4 (CG-IDP2), Tripeptide-6 (CG-CPT), Palmitoyl Pentapeptide-3, Acetyl Decapeptide-3 (Rejuline), Oligopeptide-20 (CG-IDP5), Oligopeptide-24 (CG-EDP3), Arginine
Dermaheal Cosmeceutical Mask Pack 22g
Strong antioxidant that reduces free radicals and inhibits the aging of skin cells. Keeps skin radiant and velvety-soft by actively supplying nourishment. Increases collagen and elastin level and reduces blotchiness.
DIRECTION FOR USE
Apply the mask to your clean face. Leave the mask on your face about 15~20 minutes before it begins to dry.
ACTIVE INGREDIENTS
GF sh-Oligopeptide-1 (CG-EGF), sh-Oligopeptide-2 (CG-IGF1), sh-Polypeptide-1 (CG-bFGF), sh-Polypeptide-2 (CG-TRX), Copper Tripeptide-1, Arbutin, Aloe Barbadensis Leaf Juice, Portulaca Oleracea Extract, Hamamelis Virginiana (Witch Hazel) Water, Hydrolyzed Collagen, Beta-Glucan, Panthenol
Anti-Aging Mechanism
The pathway shows how Growth Factors stimulate cells and result in cell proliferation finally. It improves skin problems from cellular level by providing simultaneous action to revive and regenerate skin cells. Cell migration, inhibition of apoptosis, gene expression and cell proliferation by Growth Factors eventually increase ECMs (Extra Cellular Matrix) such as collagen, elastin, laminin, fibronectin and hyaluronic acid etc.
STEP 1 Growth Factors binding to their interacting Growth Factor receptors
STEP 2 Phosphorylation of MAPK
STEP 3 Gene transcription
STEP 4 Cell migration, Inhibition of apoptosis, Gene expression, Cell
proliferation
Wrinkle depth was decreased by anti-aging cream treatment. Wrinkles were improved by anti-aging cream treatment.
GROWTH FACTOR STIMULATES FIBROBLAST PROLIFERATION
Upon investigation of the skin tissue in histology relaxed and irregular layers were observed. Treatment of CG-bFGF induced and densed collagen layers.
Anti-Pigmentation Mechanism
Appearance of melanin is due to an increased number of pigment cells(melanocytes) or increased production of melanin.
MELANOGENESIS VS ANTI-PIGMENTATION MECHANISM OF CG-TGP2
Inhibition of Melanosome Transfer
Biomimetic Peptides for Anti-Pigmentation
After years of research in biomimetic peptides, we have discovered many peptide candidates for anti-pigmentation and anti-inflammation.
INHIBITION OF MELANIN SYNTHESIS AFTER CG-TGP2 TREATMENT
MELANIN SYNTHESIS COMPARISON WITH VARIOUS SKIN LIGHTENING INGREDIENTS
Control: No treatment CG-TGP2: 30ug/ml Arbutin: 100ug/ml Vitamin C: 50ug/m
Phenotypic appearance of melanosome transfer in co-cultured cell lines with melanocytes( B16F10 )and keratinocyte ( HacaT ).Representative morphologies of co-cultures were observed under microscopy ( X 100 ) which was exposed for 4days with 200ng/ml α–MSH and 30µg/ml CG-TGP2.
MORPHOLOGICAL CHANGE OF MELANOCYTE CELL LINE
In cell morphology comparison, we observed the decreased melanosome formation in CG-TGP2 treated melanocyte cell line.
CLINICAL TEST OF ANTI-PIGMENTATION CREAM (CG-TGP2 AND CG-ASP)
Aged pigments and spots were decreased after using anti- pigmentation cream for 8 weeks
COLORIMETRIC MEASUREMENT
L value was increased after using anti-pigmentation cream for 8 weeks
Anti-Hair Loss / Hair Regain
DERMAHEAL TOTAL CARE SKIN SOLUTION 275g
Dermaheal Hair Conditioning Shampoo 250ml
Cleanses hair and scalp to absorb maximum active ingredients. For synergetic effects of anti-hair loss and hair regain, use Dermaheal Hair Nutrition Pack and Dermaheal Hair Concentrating Serum together.
DIRECTION FOR USE Apply to wet hair, massage scalp gently. Rinse thoroughly.
ACTIVE INGREDIENTS PT Octapeptide-2 (Prohairin-ß4), Copper Tripeptide-1, Biotin, Thuja Orientalis Extract, Polygala Tenuifolia Root Extract, Polygonum Multiflorum Root Exrtract
Dermaheal Hair Concentrating Serum 50ml
High concentration of biomimetic peptides and other active ingredients for hair nutrition intensively care scalp and hair follicle to stop hair loss and to regain hair.
DIRECTION FOR USE Drop the Hair Serum directly onto target area of scalp and massage scalp with fingertips for 2-3 minutes before bedtime to provide sufficient time for scalp to absorb the product. Allow product to remain on scalp for at least four hours before washing hair. Hair Serum should be used on a daily basis.
ACTIVE INGREDIENTSGF sh-Oligopeptide-2 (CG-IGF1), sh-Polypeptide-1 (CG-bFGF), sh-Polypeptide-9 (CG- VEGF), sh-Polypeptide-11 (CG-aFGF), Octapeptide-2 (Prohairin-Beta4), Copper Tripeptide-1, Portulaca Oleracea Extract, Sodium Hyaluronate, Polygala Tenuifolia Root Extract, Ginkgo Biloba Leaf Extract, Arginine, Polygonum Multiflorum Root Extract, Thuja Orientalis, Extract, Biotin PT Octapeptide-2 (Prohairin-Beta4). Decapeptide-4 (CG-IDP2), Acetyl Decapeptide-3 (Rejuline), Oligopeptide-41 (CG-Keramin1), Oligopeptide-20 (CG-IDP5), Copper Tripeptide-1, Portulaca Oleracea Extract, Triethanolamine, Polygala Tenuifolia Root Extract, Hydroxyethylcellulose, Arginine, Polygonum Multiflorum Root Extract, Thuja Orientalis Seed Extract
Anti-Hair Loss / Hair Regrowth Mechanism
STOP HAIR LOSS AND HAIR REGAIN MECHANISM
Anti-Hair Loss / Hair Regrowth Clinical Test Data
STOP HAIR LOSS AND HAIR REGAIN MECHANISM
SUN Protection
DERMAHEAL Sun Screen SPF 50+ PA+++ 50g
Dermaheal Sun Screen protects your skin against UVA/UVB and prevents melanin synthesis and fine lines with CG-TGP2. Smooths on with no trace of stickness. Even your skin tone and texture
DIRECTION FOR USE Apply small amount on face and neck with light circular motion. Apply 20~30 minutes before sun exposure
ACTIVE INGREDIENTSPT Oligopeptide-34 (CG-TGP2), Pentapeptide-13 (CG-ASP), Oligopeptide-24 (CG-EDP3), Tripeptide-6 (CG-CTP), Copper Tripeptide-1, Ginkgo Biloba Leaf Extract, Ulmus Davidiana Root Extract, Morus Alba Bark Extract, Glycyrrhiza (Licorice) Root Extract, Glycine Max (Soybean) Seed Extract
Cleansing & Exfoliating
Dermaheal Exfoliating Scrub Cleanser 100ml
Keeps your skin clear and soft with a facial scrub that gently exfoliates dead skin cells, removes excessive oil and blackheads and minimizes pores.
DIRECTION FOR USE
First, cleanse with Foaming Cleanser. Next, apply Exfoliating Scrub Cleanser on damp skin with circular motion to avoid eye area with fingertips. Wash off with lukewarm water. Use 2~3 times per week
ACTIVE INGREDIENTS
PT Oligopeptide-24 (CG-EDP3), Tripeptide-6 (CG- CTP), Oligoepeptide-34 (CG-TGP2), Camellia Sinensis Leaf Extract, Carica Papaya (Papaya) Fruit Extract, Poncirus Trifoliata Fruit Extract, Lavandula Angustifolia (Lavender) Extract, Monarda Didyma Leaf Extract, Mentha Piperita (Peppermint) Leaf Extract, Freesia Alba Flower Extract, Chamomilla Recutita (Matricaria) Flower Extract, Rosmarinus Officinalis (Rosemary) Flower Extract, Glycine Soja(Soybean)Oil, Protease
Dermaheal Foaming Cleanser 150ml
Rich and creamy cleanser that gently lifts dirt, make-up and impurities to leave the skin feeling soft, supple and smooth. Promotes a make- up look to be vibrant and natural. Minimizes the visibility of pores and softens imperfections for a flawless appearance.
DIRECTION FOR USE
Rinse your face with lukewarm water. Squeeze a small amount of cleanser on your palm and work into a rich lather. Massage on face with gentle circular motions. Rinse thoroughly. Use every morning and night.
ACTIVE INGREDIENTS
GF Copper Tripeptide-1, sh-Polypeptide-2 (CG-TRX), Protease PT Tripeptide-6(CG-CTP),CopperTripeptide-1,Protease
